Endocrine Abstracts

Introduction: Type 1 Gastric neuroendocrine tumors account for 70 to 80 percent of all gastric neuroendocrine tumors (G-NETs) and they are found more commonly in older adults, particularly women. They are associated with autoimmune metaplastic atrophic gastritis (AMAG) with or without pernicious anemia. Endoscopically, they are usually smaller than 1 cm and often multiple. These tumors usually present a non-aggressive evolution. Our goal is to approach the presence of risk fac...

Blackground: Parathyroid carcinoma is a malignant neoplasm affecting 0.5 to 5.0% of all patients suffering from primary hyperparathyroidism. This cancer continues to cause challenges for diagnosis and treatment because of its rarity, overlapping features with benign parathyroid disease.Case report: 50 years-old-woman, without relevant previous history. She begins to present asthenia, weakness of lower limbs, arthralgias, cramps and appearance of a painfu...

Introduction: Type 1 Gastric neuroendocrine tumors account for 70 to 80 percent of all gastric neuroendocrine tumors (G-NETs) and they are found more commonly in older adults, particularly women. They are associated with autoimmune metaplastic atrophic gastritis (AMAG) with or without pernicious anemia. They are usually smaller than 1 cm and often multiple. Our goal is to describe different characteristics of type 1 G-NETs and to study possible prognostic factors related to th...

Introduction: Pregnancy in women with type 1 diabetes mellitus (T1DM) is associated with an increased risk of adverse outcomes, so pregnancy planning in order to achieve an optimal glycemic control is essential. This control has been made possible, in part, by the widespread use of insulin analogues, especially the long-acting ones, glargine and detemir. Insulin degludec, an ultra-long-acting insulin is not currently approved for pregnant women due to the lack of randomized co...

Aim: Description of a series of children and adolescents with Primary Aldosteronism (PA) diagnosed and treated in our Outpatient Hypertension Clinic from 1994 to 2018.Methods: Review of the clinical records and of the relevant literature. Values are given as mean +s.d.Results: 16 of a total of 49 patients younger than 20 years of age referred to our Hypertension Clinic from 1994 to 2018 were diagnosed of PA (33%), while 27 (55%) we...

Aim: Comparing the effect of Faster Aspart insulin (Fiasp®) with previous insulin analogues (aspart, lispro) in type I diabetic patients with sensor-augmented pump therapy.Methods: Patients with Minimed Paradigm® insulin pumps, Enlite® sensors and Guardian® software (able to automatically stop the pump infusion to prevent hypoglycemia) were switched from previous insulin to Faster Aspart. Da...

Introduction/Aim: Transgender people often worry about side effects of their hormonal therapy, including breast cancer, which is an exceedingly rare occurrence. Hereby we present the case of a patient with an uncommon metadiabetic complication that can be easily confused with breast cancer, with the aim of raising awareness on this condition.Material and Methods: Review of the Clinical Record of the patient and of the relevant literature.<p class="ab...

Aim: To establish the effect of a supplement containing 250 mg red yeast rice extract, 525 mg berberine and 50 mg coenzyme Q10 on insulin sensitivity in patients with hypercholesterolemia and prediabetes.Methods: For this open, uncontrolled study, patients of age 30–75 years, with hypercholesterolemia (LDL cholesterol >130 mg/dl and triglycerides <300 mg/dl), and prediabetes without overt cardiovascular disease, untreated in the previous 6 m...

Introduction: The interaction between corticosteroids and protease inhibitors (PIs) is a clearly described drug interaction.Case report: A 44-year-old woman diagnosed with HIV category B3 diagnosed in 1989; severe lipodystrophy. In addition , HCV genotype IA. Bronchial asthma since 2000. Treatment with fluticasone 1 inh/24 h, salbutamol on demand, darunavir 800 mg/day and ritonavir 100 mg/day. He had known lipodystrophy since 2001 and the abdominal perim...

Introduction: Incidentally discovered adrenal masses (incidentalomas) are common and in some cases differential diagnosis could be a challenge.Case report: A 55-years old woman presented with an incidental left adrenal mass of 36mm discovered on an abdominal ultrasound. As sole background she underwent resective surgery of an ovarian serous cyst. She denied symptoms like flushing, headache, diaphoresis or palpitations. Physical examination was irrelevant...